Rabbit Secondary Antibodies
ABclonal Technology 594 Rabbit anti-Human CD6
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule The gene product is important for continuation of T cell activation This gene may be associated with susceptibility to multiple sclerosis (PMID 19525953 21849685) Multiple transcript variants encoding different isoforms have been found for this gene
Immunoreagents Inc RABBIT A-HUMAN IGG (H&L) BIO
Secondary Antibody; Rabbit anti-human IgG (H&L) - Affinity Pure, Biotin Conjugate, Host: Rabbit, Format: Liq, Label: Biotin, Applications: WB, ELISA, IHC/ICC
Immunoreagents Inc RABBIT A-HUMAN IGM MU HRP
Secondary Antibody; Rabbit anti-human IgM (mu-chain) - Affinity Pure, HRP Conjugate, Host: Rabbit, Format: Lyo, Label: HRP, Applications: WB, ELISA, IHC/ICC
ABclonal Technology PE Rabbit anti-Human CD244/2B4
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology 647 Rabbit anti-Human TIGIT
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH) The protein has been shown to bind PVR with high affinity this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses
ABclonal Technology APC Rabbit anti-Human CD38 mAb
The protein encoded by this gene is a non-lineage-restricted type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5 -diphosphate-ribose an intracellular calcium ion mobilizing messenger The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein This protein has an N-terminal cytoplasmic tail a single membrane-spanning domain and a C-terminal extracellular region with four N-glycosylation sites Crystal structure analysis demonstrates that the functional molecule is a dimer with the central portion containing the catalytic site It is used as a prognostic marker for patients with chronic lymphocytic leukemia Alternative splicing results in multiple transcript variants
ABclonal Technology 488 Rabbit anti-Human CD94
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation Several genes of the C-type lectin superfamily including members of the NKG2 family are expressed by NK cells and may be involved in the regulation of NK cell function KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus Three transcript variants encoding two different isoforms have been found for this gene
ABclonal Technology 488 Rabbit anti-Human/ FOXP3
The protein encoded by this gene is a member of the forkhead winged-helix family of transcriptional regulators Defects in this gene are the cause of immunodeficiency polyendocrinopathy enteropathy X-linked syndrome (IPEX) also known as X-linked autoimmunity-immunodeficiency syndrome Alternatively spliced transcript variants encoding different isoforms have been identified
ABclonal Technology APC Rabbit anti-Human TLR3 mAb
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity TLRs are highly conserved from Drosophila to humans and share structural and functional similarities They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents and mediate the production of cytokines necessary for the development of effective immunity The various TLRs exhibit different patterns of expression This receptor is most abundantly expressed in placenta and pancreas and is restricted to the dendritic subpopulation of the leukocytes It recognizes dsRNA associated with viral infection and induces the activation of NF-kappaB and the production of type I interferons It thus plays a role in host defense against multiple viruses
Jackson Immuno Research Labs Alexa Fluor 594-AffiniPure F(ab')2 Fragment Rabbit Anti-Human IgM Fc5µ Fragment Specific
Alexa Fluor 594-AffiniPure F(ab')2 Fragment Rabbit Anti-Human IgM Fc5µ Fragment Specific
ABclonal Technology 594 Rabbit anti-Human FceR1a
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules mediators such as histamine that are responsible for allergy symptoms are released This receptor is comprised of an alpha subunit a beta subunit and two gamma subunits The protein encoded by this gene represents the alpha subunit
ABclonal Technology 594 Rabbit anti-Human DLL4
This gene is a homolog of the Drosophila delta gene The delta gene family encodes Notch ligands that are characterized by a DSL domain EGF repeats and a transmembrane domain
ABclonal Technology 488 Rabbit anti-Human CDCP1
This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis Alternative splicing results in multiple transcript variants of this gene
ABclonal Technology 594 Rabbit anti-Human NG2
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells
ABclonal Technology 594 Rabbit anti-Human CR2/CD21
This gene encodes a membrane protein which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) Alternatively spliced transcript variants encoding different isoforms have been found for this gene